In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA

Drug-resistant tuberculosis (TB) threatens global TB control and is a major public health concern in several countries. We therefore developed a multiplex assay (LINE-TB/MDR) that is able to identify the most frequent mutations related to rifampicin (RMP) and isoniazid (INH) resistance. The assay is...

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Bibliographic Details
Main Authors: Ferreira, Sergio Luiz Montego, Costa, Elis Regina Dalla, dos Santos, Paula Gonçalves, Gomes, Harrison Magdinier, Silva, Marcia Susana Nunes, Esteves, Leonardo Souza, Oliveira, Martha Maria, Maschmann, Raquel de Abreu, Kritski, Afrânio Lineu, Suffys, Philip Noel, Rossetti, Maria Lucia Rosa
Format: Artigo
Language:Inglês
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131782/
https://ncbi.nlm.nih.gov/pubmed/24821057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-0276130469
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