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Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells

BACKGROUND AND OBJECTIVE: Tetrandrine (TET) is a bisbenzylisoquinoline alkaloid extracted from Stephania tetrandra Moore. Recent studies have suggested that TET can reduce the inflammatory response in microglia, but the mechanisms remain unclear. The aim of this study is to investigate whether TET c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dang, Yalong, Xu, Yongsheng, Wu, Wentao, Li, Weiyi, Sun, Yanran, Yang, Jing, Zhu, Yu, Zhang, Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130469/
https://ncbi.nlm.nih.gov/pubmed/25115855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102522
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