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Mast cell chymase in keloid induces profibrotic response via transforming growth factor-β(1)/Smad activation in keloid fibroblasts

This study was to examine whether mast cell chymase exists in human keloids and exerts its profibrotic effect via transforming growth factor-β(1)/Smad signaling pathway. The number of mast cells and the expression levels of chymase in keloids and normal skin were examined by immunohistochemistry ass...

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Autori principali: Dong, Xianglin, Zhang, Chuanshan, Ma, Shaolin, Wen, Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128972/
https://ncbi.nlm.nih.gov/pubmed/25120737
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