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Injurious mechanical ventilation causes kidney apoptosis and dysfunction during sepsis but not after intra-tracheal acid instillation: an experimental study

BACKGROUND: Intratracheal aspiration and sepsis are leading causes of acute lung injury that frequently necessitate mechanical ventilation (MV), which may aggravate lung injury thereby potentially increasing the risk of acute kidney injury (AKI). We compared the effects of ventilation strategies and...

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Autors principals: Kuiper, Jan Willem, Groeneveld, AB Johan, Haitsma, Jack J, Smeding, Lonneke, Begieneman, Mark PV, Jothy, Serge, Vaschetto, Rosanna, Plötz, Frans B
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119441/
https://ncbi.nlm.nih.gov/pubmed/25073618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-126
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