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A Potent HDAC Inhibitor, 1-Alaninechlamydocin, from a Tolypocladium sp. Induces G2/M Cell Cycle Arrest and Apoptosis in MIA PaCa-2 Cells
[Image: see text] The cyclic tetrapeptide 1-alaninechlamydocin was purified from a Great Lakes-derived fungal isolate identified as a Tolypocladium sp. Although the planar structure was previously described, a detailed analysis of its spectroscopic data and biological activity are reported here for...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society and American Society of Pharmacognosy
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113265/ https://ncbi.nlm.nih.gov/pubmed/24999749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500387h |
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