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Modulation of Age- and Cancer-Associated DNA Methylation Change in the Healthy Colon by Aspirin and Lifestyle

BACKGROUND: Aberrant DNA methylation in gene promoters is associated with aging and cancer, but the circumstances determining methylation change are unknown. We investigated the impact of lifestyle modulators of colorectal cancer (CRC) risk on the stability of gene promoter methylation in the coloni...

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Detalhes bibliográficos
Main Authors: Noreen, Faiza, Röösli, Martin, Gaj, Pawel, Pietrzak, Jakub, Weis, Stefan, Urfer, Patric, Regula, Jaroslaw, Schär, Primo, Truninger, Kaspar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112799/
https://ncbi.nlm.nih.gov/pubmed/24973978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju161
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