Lineage-specific function of Engrailed-2 in the progression of chronic myelogenous leukemia to T-cell blast crisis

In hematopoietic malignancies, oncogenic alterations interfere with cellular differentiation and lead to tumoral development. Identification of the proteins regulating differentiation is essential to understand how they are altered in malignancies. Chronic myelogenous leukemia (CML) is a biphasic di...

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Main Authors: Abollo-Jiménez, Fernando, Campos-Sánchez, Elena, Toboso-Navasa, Amparo, Vicente-Dueñas, Carolina, González-Herrero, Inés, Alonso-Escudero, Esther, González, Marcos, Segura, Víctor, Blanco, Óscar, Martínez-Climent, José Ángel, Sánchez-García, Isidro, Cobaleda, César
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111718/
https://ncbi.nlm.nih.gov/pubmed/24675889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28629
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