Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions

BACKGROUND: Acetylpuerarin (AP), because of its lower water solubility, shows poor absorption that hinders its therapeutic application. Thus, the aim of this study was to prepare nanoemulsions for AP, enhance its oral bioavailability, and thus improve the therapeutic effect. METHODS: The nanoemulsio...

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Main Authors: Sun, Deqing, Wei, Xinbing, Xue, Xia, Fang, Zengjun, Ren, Manru, Lou, Haiyan, Zhang, Xiumei
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111663/
https://ncbi.nlm.nih.gov/pubmed/25071371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S63777
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