Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions

BACKGROUND: Acetylpuerarin (AP), because of its lower water solubility, shows poor absorption that hinders its therapeutic application. Thus, the aim of this study was to prepare nanoemulsions for AP, enhance its oral bioavailability, and thus improve the therapeutic effect. METHODS: The nanoemulsio...

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Autori principali: Sun, Deqing, Wei, Xinbing, Xue, Xia, Fang, Zengjun, Ren, Manru, Lou, Haiyan, Zhang, Xiumei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111663/
https://ncbi.nlm.nih.gov/pubmed/25071371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S63777
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