Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions

BACKGROUND: Acetylpuerarin (AP), because of its lower water solubility, shows poor absorption that hinders its therapeutic application. Thus, the aim of this study was to prepare nanoemulsions for AP, enhance its oral bioavailability, and thus improve the therapeutic effect. METHODS: The nanoemulsio...

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Détails bibliographiques
Auteurs principaux: Sun, Deqing, Wei, Xinbing, Xue, Xia, Fang, Zengjun, Ren, Manru, Lou, Haiyan, Zhang, Xiumei
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111663/
https://ncbi.nlm.nih.gov/pubmed/25071371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S63777
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