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Advances in treatment of chronic myelogenous leukemia – new treatment options with tyrosine kinase inhibitors

Imatinib is considered standard therapy for patients with chronic myelogenous leukemia (CML), inducing a high rate of hematologic and cytogenetic responses. Despite these excellent results, several patients develop resistance to imatinib. Mechanisms of resistance are varied and include BCR-ABL1 kina...

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Bibliographic Details
Main Authors: SANTOS, FABIO P. S., RAVANDI, FARHAD
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109296/
https://ncbi.nlm.nih.gov/pubmed/20017607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428190903383427
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