GIV/Girdin is a central hub for pro-fibrogenic signalling networks during liver fibrosis

Progressive liver fibrosis is characterized by the deposition of collagen by activated hepatic stellate cells (HSCs). Activation of HSCs is a multiple receptor-driven process in which profibrotic signals are enhanced, and anti-fibrotic pathways are suppressed. Here we report the discovery of a novel...

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Bibliografiska uppgifter
Huvudupphovsmän: Lopez-Sanchez, Inmaculada, Dunkel, Ying, Roh, Yoon-Seok, Mittal, Yash, De Minicis, Samuele, Muranyi, Andrea, Singh, Shalini, Shanmugam, Kandavel, Aroonsakool, Nakon, Murray, Fiona, Ho, Samuel B., Seki, Ekihiro, Brenner, David A., Ghosh, Pradipta
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107319/
https://ncbi.nlm.nih.gov/pubmed/25043713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5451
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