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Computational and Experimental Approaches to Reveal the Effects of Single Nucleotide Polymorphisms with Respect to Disease Diagnostics

DNA mutations are the cause of many human diseases and they are the reason for natural differences among individuals by affecting the structure, function, interactions, and other properties of DNA and expressed proteins. The ability to predict whether a given mutation is disease-causing or harmless...

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Detalhes bibliográficos
Main Authors: Kucukkal, Tugba G., Yang, Ye, Chapman, Susan C., Cao, Weiguo, Alexov, Emil
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100115/
https://ncbi.nlm.nih.gov/pubmed/24886813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15069670
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