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Water Molecular System Dynamics Associated with Amyloidogenic Nucleation as Revealed by Real Time Near Infrared Spectroscopy and Aquaphotomics

The formation of amyloid fibrils proceeds via a nucleation-dependent mechanism in which nucleation phase is generally associated with a high free energy resulting in the rate-limiting step. On the basis of this kinetic feature, the nucleation is one of the most crucial phases controlling the pathoge...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chatani, Eri, Tsuchisaka, Yutaro, Masuda, Yuki, Tsenkova, Roumiana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094474/
https://ncbi.nlm.nih.gov/pubmed/25013915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101997
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