Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade

The abnormal growth of vascular smooth muscle cells (VSMCs) is considered a critical pathogenic process in inflammatory vascular diseases. We have previously demonstrated that protein phosphatase 2 A (PP2A)-mediated NF-κB dephosphorylation contributes to the anti-inflammatory properties of andrograp...

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Hlavní autoři: Chen, Yu-Ying, Hsieh, Cheng-Ying, Jayakumar, Thanasekaran, Lin, Kuan-Hung, Chou, Duen-Suey, Lu, Wan-Jung, Hsu, Ming-Jen, Sheu, Joen-Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090621/
https://ncbi.nlm.nih.gov/pubmed/25007834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05651
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