Potassium 2-(1-hydroxypentyl)-benzoate promotes long-term potentiation in Aβ(1–42)-injected rats and APP/PS1 transgenic mice

AIM: Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a new drug candidate for ischemic stroke. The aim of this study was to investigate the effects of dl-PHPB on memory deficits and long-term potentiation (LTP) impairment in animal models of Alzheimer's disease. METHODS: The expression of N...

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Autors principals: Li, Ping-ping, Wang, Wei-ping, Liu, Zhi-hui, Xu, Shao-feng, Lu, Wen-wen, Wang, Ling, Wang, Xiao-liang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088280/
https://ncbi.nlm.nih.gov/pubmed/24858312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.29
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