Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues

AIM: To verify the expression and methylation status of the MAGE-A1 and MAGE-A3 genes in colorectal cancer tissues and cancer cell lines. METHODS: We evaluated promoter demethylation status of the MAGE-A1 and MAGE-A3 genes by RT-PCR analysis and methylation-specific PCR (MS-PCR), as well as sequenci...

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Hlavní autoři: Kim, Kyung-Hee, Choi, Jin-Sung, Kim, Il-Jin, Ku, Ja-Lok, Park, Jae-Gahb
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2006
Témata:
Colorectal Cancer
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088165/
https://ncbi.nlm.nih.gov/pubmed/17007017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i35.5651
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