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Inhibition of A-Type Potassium Current by the Peptide Toxin SNX-482

SNX-482, a peptide toxin isolated from tarantula venom, has become widely used as an inhibitor of Cav2.3 voltage-gated calcium channels. Unexpectedly, we found that SNX-482 dramatically reduced the A-type potassium current in acutely dissociated dopamine neurons from mouse substantia nigra pars comp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kimm, Tilia, Bean, Bruce P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087201/
https://ncbi.nlm.nih.gov/pubmed/25009251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0339-14.2014
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