Rac2 is involved in bleomycin-induced lung inflammation leading to pulmonary fibrosis

BACKGROUND: Pulmonary fibrotic diseases induce significant morbidity and mortality, for which there are limited therapeutic options available. Rac2, a ras-related guanosine triphosphatase expressed mainly in hematopoietic cells, is a crucial molecule regulating a diversity of mast cell, macrophage,...

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Détails bibliographiques
Auteurs principaux: Arizmendi, Narcy, Puttagunta, Lakshmi, Chung, Kerri L, Davidson, Courtney, Rey-Parra, Juliana, Chao, Danny V, Thebaud, Bernard, Lacy, Paige, Vliagoftis, Harissios
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082672/
https://ncbi.nlm.nih.gov/pubmed/24970330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-15-71
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