Characteristics and outcomes of patients with chronic myeloid leukemia and T315I mutation following failure of imatinib mesylate therapy

Chronic myeloid leukemia (CML) with T315I mutation has been reported to have poor prognosis. We analyzed 27 patients with T315I, including 20 who developed T315I after imatinib failure (representing 11% of 186 patients with imatinib failure), and 7 of 23 who developed new mutations after second tyro...

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Bibliographic Details
Main Authors: Jabbour, Elias, Kantarjian, Hagop, Jones, Dan, Breeden, Megan, Garcia-Manero, Guillermo, O'Brien, Susan, Ravandi, Farhad, Borthakur, Gautam, Cortes, Jorge
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2008
Subjects:
Clinical Trials and Observations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081375/
https://ncbi.nlm.nih.gov/pubmed/18403620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-123950
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