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TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception

Motivation: An estimated 10–30% of clinically recognized conceptions are aneuploid, leading to spontaneous miscarriages, in vitro fertilization failures and, when viable, severe developmental disabilities. With the ongoing reduction in the cost of genotyping and DNA sequencing, the use of high-densi...

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Hlavní autoři: Kermany, Amir R., Segurel, Laure, Oliver, Tiffany R., Przeworski, Molly
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080739/
https://ncbi.nlm.nih.gov/pubmed/24659032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu159
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