Molecular basis of aflatoxin-induced mutagenesis—role of the aflatoxin B(1)-formamidopyrimidine adduct

Aflatoxin B(1) (AFB(1)) is a known carcinogen associated with early-onset hepatocellular carcinoma (HCC) and is thought to contribute to over half a million new HCCs per year. Although some of the fundamental risk factors are established, the molecular basis of AFB(1)-induced mutagenesis in primate...

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Bibliographic Details
Main Authors: Lin, Ying-Chih, Li, Liang, Makarova, Alena V., Burgers, Peter M., Stone, Michael P., Lloyd, R. Stephen
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076807/
https://ncbi.nlm.nih.gov/pubmed/24398669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu003
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