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BAG6 regulates the quality control of a polytopic ERAD substrate
BAG6 participates in protein quality control and, here, we address its role in endoplasmic-reticulum-associated degradation (ERAD) by using the polytopic membrane protein OpD, an opsin degron mutant. Both BAG6 knockdown and BAG6 overexpression delay OpD degradation; however, our data suggest that th...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4075357/ https://ncbi.nlm.nih.gov/pubmed/24806960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.145565 |
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