Hyperbaric oxygen improves engraftment of ex-vivo expanded and gene transduced human CD34(+) cells in a murine model of umbilical cord blood transplantation

Delayed engraftment and graft failure represent major obstacles to successful umbilical cord blood (UCB) transplantation. Herein, we evaluated the use of hyperbaric oxygen (HBO) therapy as an intervention to improve human UCB stem/progenitor cell engraftment in an immune deficient mouse model. Six-t...

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Bibliographic Details
Main Authors: Aljitawi, Omar S., Xiao, Yinghua, Eskew, Jeff D., Parelkar, Nikhil K., Swink, Megan, Radel, Jeff, Lin, Tara L., Kimler, Bruce F., Mahnken, Jonathan D., McGuirk, Joseph P., Broxmeyer, Hal E., Vielhauer, George
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075130/
https://ncbi.nlm.nih.gov/pubmed/23953010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2013.07.013
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