A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12

Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither chemotherapeutic nor targeted therapeutic approaches h...

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Bibliographic Details
Main Authors: Burger, Alexa, Vasilyev, Aleksandr, Tomar, Ritu, Selig, Martin K., Nielsen, G. Petur, Peterson, Randall T., Drummond, Iain A., Haber, Daniel A.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Limited 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073279/
https://ncbi.nlm.nih.gov/pubmed/24311731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013128
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