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Aberrant Proliferation of Differentiating Alveolar Cells Induces Hyperplasia in Resting Mammary Glands of SV40-TAg Transgenic Mice
WAP-T1 transgenic mice express SV40-TAg under control of the whey acidic protein (WAP) promoter, which directs activity of this strong viral oncogene to luminal cells of the mammary gland. Resting uniparous WAP-T1 glands develop hyperplasia composed of TAg positive cells prior to appearance of advan...
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Auteurs principaux: | , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Frontiers Media S.A.
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071642/ https://ncbi.nlm.nih.gov/pubmed/25019062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00168 |
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