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Diffusion basis spectrum imaging detects and distinguishes coexisting subclinical inflammation, demyelination, and axonal injury in experimental autoimmune encephalomyelitis mice

Clinicopathological paradox has significantly hampered the effective assessment of the efficacy of therapeutic intervention of multiple sclerosis. The neuroimaging biomarkers of tissue injury could guide a more effective treatment by accurately reflecting the underlying subclinical pathologies. Diff...

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Bibliographic Details
Main Authors: Wang, Xiaojie, Cusick, Matthew F., Wang, Yong, Sun, Peng, Libbey, Jane E., Trinkaus, Kathryn, Fujinami, Robert S., Song, Sheng-Kwei
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071074/
https://ncbi.nlm.nih.gov/pubmed/24816651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3129
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