Inhibition of Let7c MicroRNA Is Neuroprotective in a Rat Intracerebral Hemorrhage Model

Intracerebral hemorrhage (ICH) is a devastating neurological disease with a grave prognosis. We evaluated microRNA (miRNA) expression after ICH and evaluated Let7c as a therapeutic target. We harvested hemorrhagic brain 24 hours after collagenase induced ICH in the rat. Microarray analysis was perfo...

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Autors principals: Kim, Jeong-Min, Lee, Soon-Tae, Chu, Kon, Jung, Keun-Hwa, Kim, Jin Hee, Yu, Jung-Suk, Kim, Soyun, Kim, So Hee, Park, Dong-Kyu, Moon, Jangsup, Ban, Jaejun, Kim, Manho, Lee, Sang Kun, Roh, Jae-Kyu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068982/
https://ncbi.nlm.nih.gov/pubmed/24959881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097946
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