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Calcineurin/Nuclear Factor of Activated T Cells–Coupled Vanilliod Transient Receptor Potential Channel 4 Ca(2+) Sparklets Stimulate Airway Smooth Muscle Cell Proliferation

Proliferation of airway smooth muscle cells (ASMCs) contributes to the remodeling and irreversible obstruction of airways during severe asthma, but the mechanisms underlying this disease process are poorly understood. Here we tested the hypothesis that Ca(2+) influx through the vanilliod transient r...

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Autors principals: Zhao, Limin, Sullivan, Michelle N., Chase, Marlee, Gonzales, Albert L., Earley, Scott
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068915/
https://ncbi.nlm.nih.gov/pubmed/24392954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0416OC
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