Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

Known genetic loci explain only a small proportion of the familial relative risk of colorectal cancer (CRC). We conducted the largest genome-wide association study in East Asians with 14,963 CRC cases and 31,945 controls and identified six new loci associated with CRC risk (P = 3.42 × 10(−8) to 9.22...

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Detalhes bibliográficos
Main Authors: Zhang, Ben, Jia, Wei-Hua, Matsuda, Koichi, Kweon, Sun-Seog, Matsuo, Keitaro, Xiang, Yong-Bing, Shin, Aesun, Jee, Sun Ha, Kim, Dong-Hyun, Cai, Qiuyin, Long, Jirong, Shi, Jiajun, Wen, Wanqing, Yang, Gong, Zhang, Yanfeng, Li, Chun, Li, Bingshan, Guo, Yan, Ren, Zefang, Ji, Bu-Tian, Pan, Zhi-Zhong, Takahashi, Atsushi, Shin, Min-Ho, Matsuda, Fumihiko, Gao, Yu-Tang, Oh, Jae Hwan, Kim, Soriul, Ahn, Yoon-Ok, Chan, Andrew T, Chang-Claude, Jenny, Slattery, Martha L., Gruber, Stephen B., Schumacher, Fredrick R., Stenzel, Stephanie L., Casey, Graham, Kim, Hyeong-Rok, Jeong, Jin-Young, Park, Ji Won, Li, Hong-Lan, Hosono, Satoyo, Cho, Sang-Hee, Kubo, Michiaki, Shu, Xiao-Ou, Zeng, Yi-Xin, Zheng, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068797/
https://ncbi.nlm.nih.gov/pubmed/24836286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2985
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