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Ensemble Generation and the Influence of Protein Flexibility on Geometric Tunnel Prediction in Cytochrome P450 Enzymes

Computational prediction of ligand entry and egress paths in proteins has become an emerging topic in computational biology and has proven useful in fields such as protein engineering and drug design. Geometric tunnel prediction programs, such as Caver3.0 and MolAxis, are computationally efficient m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kingsley, Laura J., Lill, Markus A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067289/
https://ncbi.nlm.nih.gov/pubmed/24956479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099408
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