Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals

BACKGROUND: The MPER region of the HIV-1 envelope glycoprotein gp41 is targeted by broadly neutralizing antibodies. However, the localization of this epitope in a hydrophobic environment seems to hamper the elicitation of these antibodies in HIV infected individuals. We have quantified and character...

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Bibliografski detalji
Glavni autori: Molinos-Albert, Luis M, Carrillo, Jorge, Curriu, Marta, Rodriguez de la Concepción, Maria L, Marfil, Silvia, García, Elisabet, Clotet, Bonaventura, Blanco, Julià
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067070/
https://ncbi.nlm.nih.gov/pubmed/24909946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-44
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