Cartilage Dysfunction in ALS Patients as Side Effect of Motion Loss: 3D Mechano-Electrochemical Computational Model

Amyotrophic lateral sclerosis (ALS) is a debilitating motor neuron disease characterized by progressive weakness, muscle atrophy, and fasciculation. This fact results in a continuous degeneration and dysfunction of articular soft tissues. Specifically, cartilage is an avascular and nonneural connect...

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Hlavní autoři: Manzano, Sara, Gaffney, Eamonn A., Doblaré, Manuel, Hamdy Doweidar, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065674/
https://ncbi.nlm.nih.gov/pubmed/24991537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/179070
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