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On the use of low-frequency normal modes to enforce collective movements in refining macromolecular structural models

As more and more structures of macromolecular complexes get solved in different conditions, it has become apparent that flexibility is an inherent part of their biological function. Normal mode analysis using simplified models of proteins such as the elastic network model has proved very effective i...

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Hlavní autoři: Delarue, Marc, Dumas, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC406448/
https://ncbi.nlm.nih.gov/pubmed/15096585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400301101
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