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On the use of low-frequency normal modes to enforce collective movements in refining macromolecular structural models
As more and more structures of macromolecular complexes get solved in different conditions, it has become apparent that flexibility is an inherent part of their biological function. Normal mode analysis using simplified models of proteins such as the elastic network model has proved very effective i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406448/ https://ncbi.nlm.nih.gov/pubmed/15096585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400301101 |
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