TMEM16A knockdown abrogates two different Ca(2+)-activated Cl(−) currents and contractility of smooth muscle in rat mesenteric small arteries

The presence of Ca(2+)-activated Cl(−) channels (CaCCs) in vascular smooth muscle cells (SMCs) is well established. Their molecular identity is, however, elusive. Two distinct Ca(2+)-activated Cl(−) currents (I (Cl(Ca))) were previously characterized in SMCs. We have shown that the cGMP-dependent I...

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Bibliographic Details
Main Authors: Dam, Vibeke Secher, Boedtkjer, Donna M. B., Nyvad, Jakob, Aalkjaer, Christian, Matchkov, Vladimir
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2013
Subjects:
Ion Channels, Receptors and Transporters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062836/
https://ncbi.nlm.nih.gov/pubmed/24162234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-013-1382-1
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