Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia

BACKGROUND: Aberrant DNA methylation is frequently found in human malignancies including acute myeloid leukemia (AML). While most studies focus on later disease stages, the onset of aberrant DNA methylation events and their dynamics during leukemic progression are largely unknown. METHODS: We screen...

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Main Authors: Sonnet, Miriam, Claus, Rainer, Becker, Natalia, Zucknick, Manuela, Petersen, Jana, Lipka, Daniel B, Oakes, Christopher C, Andrulis, Mindaugas, Lier, Amelie, Milsom, Michael D, Witte, Tania, Gu, Lei, Kim-Wanner, Soo-Zin, Schirmacher, Peter, Wulfert, Michael, Gattermann, Norbert, Lübbert, Michael, Rosenbauer, Frank, Rehli, Michael, Bullinger, Lars, Weichenhan, Dieter, Plass, Christoph
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062060/
https://ncbi.nlm.nih.gov/pubmed/24944583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm551
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