Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion

We previously reported that phospholipase C-related catalytically inactive protein (PRIP)-knockout mice exhibited hyperinsulinemia. Here, we investigated the role of PRIP in insulin granule exocytosis using Prip-knockdown mouse insulinoma (MIN6) cells. Insulin release from Prip-knockdown MIN6 cells...

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Bibliografiske detaljer
Main Authors: Asano, Satoshi, Nemoto, Tomomi, Kitayama, Tomoya, Harada, Kae, Zhang, Jun, Harada, Kana, Tanida, Isei, Hirata, Masato, Kanematsu, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058080/
https://ncbi.nlm.nih.gov/pubmed/24812354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147591
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