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Study on Biopharmaceutics Classification and Oral Bioavailability of a Novel Multikinase Inhibitor NCE for Cancer Therapy

Specific biopharmaceutics classification investigation and study on phamacokinetic profile of a novel drug candidate (2-methylcarbamoyl-4-{4-[3- (trifluoromethyl) benzamido] phenoxy} pyridinium 4-methylbenzenesulfonate monohydrate, NCE) were carried out. Equilibrium solubility and intrinsic dissolut...

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Bibliographic Details
Main Authors: Yang, Yang, Fan, Chun-Mei, He, Xuan, Ren, Ke, Zhang, Jin-Kun, He, Ying-Ju, Yu, Luo-Ting, Zhao, Ying-Lan, Gong, Chang-Yang, Zheng, Yu, Song, Xiang-Rong, Zeng, Jun
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057667/
https://ncbi.nlm.nih.gov/pubmed/24776763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15057199
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