PPARγ Negatively Regulates T Cell Activation to Prevent Follicular Helper T Cells and Germinal Center Formation

Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor that regulates lipid and glucose metabolism. Although studies of PPARγ ligands have demonstrated its regulatory functions in inflammation and adaptive immunity, its intrinsic role in T cells and autoimmunity has yet t...

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Hlavní autoři: Park, Hong-Jai, Kim, Do-Hyun, Choi, Jin-Young, Kim, Won-Ju, Kim, Ji Yun, Senejani, Alireza G., Hwang, Soo Seok, Kim, Lark Kyun, Tobiasova, Zuzana, Lee, Gap Ryol, Craft, Joseph, Bothwell, Alfred L. M., Choi, Je-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055678/
https://ncbi.nlm.nih.gov/pubmed/24921943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099127
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