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microRNAs join the p53 network — another piece in the tumour-suppression puzzle

Several recent studies have found a conserved microRNA (miRNA) family, the miR-34s, to be direct transcriptional targets of p53. miR-34 activation can recapitulate elements of p53 activity, including induction of cell-cycle arrest and promotion of apoptosis, and loss of miR-34 can impair p53-mediate...

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Detaylı Bibliyografya
Asıl Yazarlar: He, Lin, He, Xingyue, Lowe, Scott W., Hannon, Gregory J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053212/
https://ncbi.nlm.nih.gov/pubmed/17914404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2232
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