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Antagonistic actions of Rcor proteins regulate LSD1 activity and cellular differentiation

Lysine-specific demethylase 1 (LSD1) demethylates nucleosomal histone H3 lysine 4 (H3K4) residues in collaboration with the corepressor CoREST/REST corepressor 1 (Rcor1) and regulates cell fates by epigenetically repressing gene targets. The balanced regulation of this demethylase, if any, is howeve...

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Detalhes bibliográficos
Main Authors: Upadhyay, Ghanshyam, Chowdhury, Asif H., Vaidyanathan, Bharat, Kim, David, Saleque, Shireen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050576/
https://ncbi.nlm.nih.gov/pubmed/24843136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404292111
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