Short-term high-fat-and-fructose feeding produces insulin signaling alterations accompanied by neurite and synaptic reduction and astroglial activation in the rat hippocampus

Chronic consumption of high-fat-and-fructose diets (HFFD) is associated with the development of insulin resistance (InsRes) and obesity. Systemic insulin resistance resulting from long-term HFFD feeding has detrimental consequences on cognitive performance, neurogenesis, and long-term potentiation e...

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Hauptverfasser: Calvo-Ochoa, Erika, Hernández-Ortega, Karina, Ferrera, Patricia, Morimoto, Sumiko, Arias, Clorinda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050245/
https://ncbi.nlm.nih.gov/pubmed/24667917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.48
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