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The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation
The nuclear receptor, REV-ERBα, has a key role in circadian rhythms and requires heme as its ligand. The present study determined whether the heme precursor, 5-aminolevulinic acid (ALA), affects REV-ERBα and its target genes. When exposed to ALA, the human lung diploid cell line, WI-38, exhibited ac...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050196/ https://ncbi.nlm.nih.gov/pubmed/24918048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.03.010 |
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