C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

Intronic expansion of a hexanucleotide GGGGCC repeat in the chromosome 9 open reading frame 72 (C9ORF72) gene is the major cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. However, the cellular function of the C9ORF72 protein remains unknown. Here, we demonstrate th...

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Xehetasun bibliografikoak
Egile Nagusiak: Farg, Manal A., Sundaramoorthy, Vinod, Sultana, Jessica M., Yang, Shu, Atkinson, Rachel A.K., Levina, Vita, Halloran, Mark A., Gleeson, Paul A., Blair, Ian P., Soo, Kai Y., King, Anna E., Atkin, Julie D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049310/
https://ncbi.nlm.nih.gov/pubmed/24549040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu068
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