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Profilin phosphorylation as a VEGFR effector in angiogenesis

Vascular endothelial growth factor (VEGF) signalling induces embryonic vascular development and angiogenesis in adult tissues. Direct phosphorylation of the actin-binding protein profilin by VEGF receptors is now shown to increase its affinity for actin, and to be essential for adult but not embryon...

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Detalhes bibliográficos
Main Authors: Simons, Michael, Schwartz, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047563/
https://ncbi.nlm.nih.gov/pubmed/23033049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2596
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