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Fever-Range Whole-body Thermotherapy Combined With Oxaliplatin: A Curative Regimen in a Preclinical Breast Cancer Model

PURPOSE: Studies were conducted to test whether fever-range whole body hyperthermia, rationally combined with oxaliplatin chemotherapy, would boost its efficacy without substantial toxicity. MATERIALS AND METHODS: The effect of heat on oxaliplatin cytotoxicity, cellular uptake, and platinum-DNA addu...

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Bibliographic Details
Main Authors: Rowe, RW, Strebel, FR, Proett, JM, Deng, W, Chan, D, He, G, Siddik, ZH, Bull, JMC
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045248/
https://ncbi.nlm.nih.gov/pubmed/20707651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02656736.2010.483635
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