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Genetic determinants and cellular constraints in noisy gene expression
In individual cells, transcription is a random process obeying single-molecule kinetics. Often, it occurs in a bursty, intermittent manner. The frequency and size of these bursts affect the magnitude of temporal fluctuations in mRNA and protein content within a cell, creating variation or “noise” in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4045091/ https://ncbi.nlm.nih.gov/pubmed/24311680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1242975 |
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