Helicobacter pylori CagL Y58/E59 Mutation Turns-Off Type IV Secretion-Dependent Delivery of CagA into Host Cells

The type IV secretion system (T4SS) is a major virulence determinant of the gastric pathogen Helicobacter pylori. The CagL protein is a specialized adhesin of the corresponding T4SS pilus, which establishes initial contact with the integrin β1 receptor on host target cells. Recent studies proposed t...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Tegtmeyer, Nicole, Lind, Judith, Schmid, Benedikt, Backert, Steffen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Formal Comment
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043526/
https://ncbi.nlm.nih.gov/pubmed/24893039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097782
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