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Tob deficiency superenhances osteoblastic activity after ovariectomy to block estrogen deficiency-induced osteoporosis

Tob (transducer of erbB2) is a member of antiproliferative family proteins and acts as a bone morphogenic protein inhibitor as well as a suppressor of proliferation in T cells, which have been implicated in postmenopausal bone loss. To determine the effect of Tob deficiency on estrogen deficiency-in...

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Main Authors: Usui, Michihiko, Yoshida, Yutaka, Tsuji, Kunikazu, Oikawa, Kaoru, Miyazono, Kohei, Ishikawa, Isao, Yamamoto, Tadashi, Nifuji, Akira, Noda, Masaki
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC404100/
https://ncbi.nlm.nih.gov/pubmed/15100414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0303093101
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